| Model (body), release period | Generation | Engine model |
|---|---|---|
| Toyota Highlander (XU20) 2000 – 2007 | 1st generation | 2AZ-FE / 1MZ-FE / 3MZ-FE |
| Toyota Highlander (XU40) 2007 – 2013 | 2nd generation | 1AR-FE / 2GR-FE / 3MZ-FE |
| Toyota Highlander (XU50) 2013 – 2020 | 3rd generation | 1AR-FE / 2GR-FE / 2GR-FXS / 2GR-FKS |
| Toyota Highlander (XU70) 2019 – present | 4th generation | T24A-FTS / A25A-FXS / 2GR-FKS |